Of all the seven quarter finalists in this year’s Champions League, it’s Milan who have played most times against Barça in Europe.
APOEL and Olympique de Marseille, in contrast, have never faced Barça in European competitions.
The Italians have faced Barça eight times in Europe, with honours pretty even. The last time the two met was in the group stages earlier this season, when they drew 2-2 in the Camp Nou and Barça won 2-3 in Italy. Previously, Barça knocked Milan out in the 2005/6 semi-final, but when the two have come up against each other in European finals, it's been Milan who have come out on top, winning the 1994 Champions League final 4-1 and the European Super Cup in 1989 2-1.
The Portuguese team have played Barça on just three occasions. The first time was in the 1960/61 European Cup Final, which ended 3-2 for the Lisbon club in Bern. Thirty-one years later, Barça beat Benfica in the group stages on their way to their famous Wembley victory and the last time the two teams met was in the 2006 Champions League quarter finals when Frank Rijkaard's team won 2-0 at the Camp Nou to ensure a place in the next round.
The German giants have also played Barça three times in European competitions, with 1 win for Barça and 2 for Bayern. The most recent game went Barça's way in 2008, when Pep Guardiola's team won 4-0 at home and drew 1-1 in Munich in the quarter finals. Before that, Bayern had won in the group stage of the 98/99 Champions League and in the semi final of the 1996 UEFA Cup.
It was only last season that Barça and Real Madrid met in the Champions League semi-final, when a memorable 0-2 win at the Bernabeu and a 1-1 draw at the Camp Noou saw Pep Guardiola through to his second Champions League final in two years. A decade previously, it had been the other way round, with Madrid going through after the same results in their favour. The two had previously each enjoyed a victory in the early sixties, when Barça became the first team to knock Madrid out of Europe thanks to Evaristo's famous header.
If the draw throws up another game against Chelsea, memories will surely go back to that famous night at Stamford Bridge in the 2009 semi final, when Andres Iniesta's last gasp strike took Barça to the Rome final. There have been five meetings in all between the two teams, with Barça leading on 3 wins against Chelsea's two.
Neither the Cypriot nor the French qualifiers have ever faced Barça, with APOEL very much the surprise package and making their first appearance at this stage of the competition, whilst Marseilles won the title back in 1994, but have not made it this far since then. (via FCBarcelona.com)