Last season produced a very similar situation to the present one. Barça won at the Calderón, but an injured Messi missed the following game with the Asturians. Without the Argentinian on the pitch, Barça has not lost since 2009.
Last year, an Ujfalusi tackle on Messi meant the latter had to retire from the game, which Barça still won 2-1. Like last year, the next game was against Sporting at the Camp Nou, which was won thanks to a goal from Villa (1-0).
Leo Messi has only missed three of the 44 games played so far this season. They were the cup matches with L'Hospitalet, which FCB won 1-0 and 9-0, and the 4-0 win against BATE Borisov in the Champions League groups stage. Three wins out of three.
The Argentinian also came on as a substitute in two other matches, the one at Anoeta in the league (2-2) and the first leg of the cup tie with Osasuna (4-0), where he even scored two of the goals. He has started the other 39 official matches this season.
Last season, Messi missed six games (Sporting Gijón, Athletic Bilbao, Ceuta, Levante, Deportivo and Malaga), five of which were won and the other drawn. There were no losses without Messi in 2009/10 either, and in fact the last time the team has lost without him in the side was way back in 2008/09, when they lost 1-0 at home to Osasuna on May 23, a game in which several big names were rested ahead of the Champions League final in Rome. (via FCBarcelona.com)